Cutting Edge: Activation of Virus-Specific CD4 T Cells throughout g-Herpesvirus Latency
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Cutting edge: activation of virus-specific CD4 T cells throughout γ-herpesvirus latency.
CD4 T cells are essential for immune control of γ-herpesvirus latency. We previously identified a murine MHC class II-restricted epitope in γ-herpesvirus-68 gp150 (gp150(67-83)I-A(b)) that elicits CD4 T cells that are maintained throughout long-term infection. However, it is unknown whether naive cells can be recruited into the antiviral CD4 T cell pool during latency. In this study, we generat...
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تاریخ انتشار 2011